MCAS: What meds helped you most?

I just gut diagnosed MCAS from IMD Berlin laboratory and started a treatment two weeks ago.

I am wondering what medications helped you most and what combinations did you end up taking?

IMD Berlin officially recommends the following possible cocktail:

Brands might be specific for Germany or Europe.


H1-Antihistaminikum – Desloratadin: or Rupafin (up to 4 times the regular dosage possible)

H2-Antihistaminikum - Famotidin: Ranitidin: 3 x 150 mg

Vitamin C...

MCAS: What meds helped you most?